1. Serum sickness arises seven to fourteen days after the therapy has begun.2. Later during the treatment, some patients develop serum sickness or immune complex glomerulonephritis. 3. The antivenin can cause an immune reaction called serum sickness . 4. Penicillin can also induce serum sickness or a serum sickness -like reaction in some individuals. 5. Penicillin can also induce serum sickness or a serum sickness-like reaction in some individuals. 6. Another type of delayed allergic reaction is serum sickness . 7. Serum sickness is primarily caused by the antibodies clumping during infusion and triggering the complement cascade.8. This typifies the response to injection of foreign antigen sufficient to lead to the condition of serum sickness . 9. There is also a potential risk for hypersensitivity reactions, and serum sickness , especially from gamma globulin of non-human origin. 10. Injection of horse serum into humans as used in antitoxin can cause hypersensitivity, commonly referred to as serum sickness .